Blar i forfatter "Isaksen, Victoria Therese"

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    • Betydning av lett patologiske leverenzymer i normalbefolkningen. Tromsøundersøkelsen. 

      Isaksen, Victoria Therese (Master thesis; Mastergradsoppgave, 2014-06-01)
      Transaminaser og gamma-GT er alle markører på leversykdom. Høye plasmanivåer av transaminaser tyder på levercelleskade, mens GT er primært en galleveismarkør. Non-alkoholisk fettleversykdom er vist å gi økte verdier av disse markørene. I Tromsø 6 var varslingsgrensa for videre medisinsk oppfølging av leverprøvene satt til to ganger øvre normalgrense. Formålet med oppgaven er å undersøke om varslingsgrensa ...

    • Correlations between modest weight loss and leptin to adiponectin ratio, insulin and leptin resensitization in a small cohort of Norwegian individuals with obesity 

      Isaksen, Victoria Therese; Larsen, Maria; Goll, Rasmus; Paulssen, Eyvind Jakob; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-02)
      Background - Weight loss is important to reduce the risk of metabolic complications in obese individuals, in whom dysregulated adipokines play a central role. This study aims to investigate whether dysregulated adipokines and postprandial triglycerides (TG) improve with a modest weight loss.<p> <p>Methods - Individuals with obesity (BMI ≥ 30 kg/m2) were recruited among patients at the University ...

    • Early Markers of Metabolic Dysregulation in Obese Individuals - Identification at Baseline and Effect of Modest Weight Loss 

      Isaksen, Victoria Therese (Doctoral thesis; Doktorgradsavhandling, 2023-11-15)
      <p><i>Background:</i> Evidence suggests that the link between obesity and chronic lifestyle disease is chronic, low-grade inflammation. Leptin and adiponectin play principal roles in inducing inflammation and promoting insulin resistance, resulting in metabolic syndrome. Our study aimed to find clinically feasible biologic markers to identify metabolically dysregulated obese individuals and to study ...

    • Hepatic Steatosis detected by Hepatorenal Index in Ultrasonography as a Predictor of Insulin Resistance in Obese Subjects 

      Isaksen, Victoria Therese; Larsen, Maria Arlen; Goll, Rasmus; Florholmen, Jon; Paulssen, Eyvind Jakob (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-20)
      BACKGROUND: The metabolic syndrome is a worldwide health issue, with non-alcoholic fatty liver disease (liver steatosis) being one of its features, particularly closely related to insulin resistance. This study aims to investigate whether quantification of hepatic steatosis by abdominal ultrasonography, using hepatorenal index, is a feasible tool for the prediction of insulin resistance, and thus ...

    • Hepatic steatosis detected by ultrasonography as a predictor of insulin resistance in obese patients 

      Isaksen, Victoria Therese (Master thesis; Mastergradsoppgave, 2014-10-31)
      Non-alcoholic fatty liver disease is closely related to the Metabolic syndrome. A significant feature of NAFLD is the presence of hepatic steatosis, which can be assessed by ultrasonography, by measuring the hepatorenal index (HRI), a comparison of liver and kidney acoustic echo densities. This study aims to investigate if HRI can predict insulin resistance. Ninety participants from the obesity ...

    • Postprandial leptin and adiponectin in response to sugar and fat in obese and normal weight individuals 

      Larsen, Maria Arlén; Isaksen, Victoria Therese; Paulssen, Eyvind Jakob; Goll, Rasmus; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-11)
      <p><i>Purpose - </i>Adipokines produced by white adipose tissue are central in the development of lifestyle diseases. Individuals in industrialized countries spend a substantial part of life in the non-fasting, postprandial state, which is associated with increased oxidation and inflammation. The aim was to study postprandial adiponectin and leptin levels after an oral fat tolerance test (OFTT) and ...